Unlike conventional radiation therapy that is typically delivered to patients over weeks, FLASH radiation can deliver an ultra-concentrated dose in less than one second. A major objective is to understand the biology of this next-generation radiation modality with the goal of facilitating its clinical translation.
Immune effects
Conventional radiation can impact the immune system and improve immunotherapy by activating innate immune signaling pathways. We seek to characterize and investigate the immunogenic effects of FLASH radiation.
Normal tissue effects
FLASH radiation has approximately similar anti-tumor efficacy compared to conventional radiation but is associated with significantly less normal tissue toxicity. Center scientists are working together to investigate the biology behind this normal tissue-sparing effect.
